Mus musculus

UniProt Data

Accession A1EGX6 [ UniProt ]
Name FSCB_MOUSE
Description Fibrous sheath CABYR-binding protein
Species Mus musculus
Sequence Length1074

Enzyme Annotations (0)

    GO Annotations

    Cellular component (2)

    • GO:0035686 Sperm fibrous sheath
      A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.
    • GO:0097228 Sperm principal piece
      The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.

    Molecular function (2)

    • GO:0005509 Calcium ion binding
      Interacting selectively and non-covalently with calcium ions (Ca2+).
    • GO:0005515 Protein binding
      Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

    Biological process (1)

    None predicted

    Protein Sequence

    >A1EGX6
    MEECEEPEEPISLGRQEYRRRRRPSQPMVDKSQQTEITEKRKAMASVQPPAPKATHSIGNIPGSKDNYSRKEYESLRLSS
    QLQKTLMKRKHVQDMTDKSLQTEPIVEEKVEVIFIDKTLKLEENTAGVGEIAPELPQSIPEVEIPTSRPTSHLIDRSQQT
    SCTGDWSLIYICPKEKVDKEQQTYFSELEIIIRSIPGSSMTKSKEETIPIAQEDPLVEINGSLEIEVLSPEELPDVMMSF
    TEGEISGELQALSNGEATVKGELFLTEEIPIQAPSPAEETSAAETATTTAKDVVDIQAPPADKLSSVEAPADISPTLVQG
    ALSDKPSDQQYPQGTEMAPSELPVEDLDPFSEEVLEKVQALTTDSMLEDLGIAESTIAEETSGKVQHPLSEETSKEVPAE
    VHFPIAADFEESAILINEKFATDEVFEEYKPPIIEEVSADKATAEVQPPSAEDASEEVASSEVLPPSTEQGTVEDLTAEV
    LSTPTEEGPTEVPPQPTEEGPAEVPPPLSEEGPAEVPPAPAEEAPAEVLPPPAEEAPAEVPPPLTEEGPAEVPPPLTEEG
    PAEVPLAPAEEVPAEFLPPPAEEVPAEVPPPLTEEGPAEVPPPLTEEGPEEVPPLPAEEAPTKVPPSPAEKGSAEVSPPQ
    TEEGPAEVPPPPAEEFPTEVPSSSAEEGSSEVPLPPTAERPEEAPPPATEEAPVEVLPPATEEAPVEVLPPATEEAPVEV
    QSPAAEEGLAEVPPPPTEESPTHDVPTEVQVPQAKESPGQVLPLSGESTAEEASAQVQPPSFEKAPLESLPLEEVEKIHL
    DNLPFEVQPLPTEDIAIGVPAESQALPADENPAREDTVETQPSSFEGAPIAENPIEAPLPASEADTGREDSAVHPSSLGP
    TDEAPAEIQILQTDDIPTEMSPVENQPLPAEEGFPEVVSEEEATAAEVRFPLSEGAPAQEATVEAQLTSVEESPKRASVD
    VQPLSPETPVEESPGVDLPLKTNEVTMQEFRVEKMPAEDSLPPSEQTPADQVLLKEHRLSQVADISEKELESTTLTSDKM
    SEGIDSVPEDVSGTKDDQISTFKIEGTIKIELKN