Genome3D
Escherichia coli K-12

gnd 6-phosphogluconate dehydrogenase, decarboxylating

UniProt Data

Accession P00350 [ UniProt ]
Name 6PGD_ECOLI
Description 6-phosphogluconate dehydrogenase, decarboxylating
Species Escherichia coli K-12
Sequence Length468

Enzyme Annotations (1)

  • EC:1.1.1.44 Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating).
    6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.

GO Annotations

Cellular component (1)

None predicted

Molecular function (4)

  • GO:0004616 Phosphogluconate dehydrogenase (decarboxylating) activity
    Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
  • GO:0004616 Phosphogluconate dehydrogenase (decarboxylating) activity
    Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
  • GO:0042802 Identical protein binding
    Interacting selectively and non-covalently with an identical protein or proteins.
  • GO:0042803 Protein homodimerization activity
    Interacting selectively and non-covalently with an identical protein to form a homodimer.

Biological process (1)

None predicted

Protein Sequence

>P00350
MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGT
DAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQTFTEWNNGELSSYLIDITKDIFT
KKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEK
VRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADDY
QQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDKEGVFHTEWLD