Mus musculus

UniProt Data

Accession Q62415 [ UniProt ]
Name ASPP1_MOUSE
Description Apoptosis-stimulating of p53 protein 1
Species Mus musculus
Sequence Length1087

Enzyme Annotations (0)

    GO Annotations

    Cellular component (5)

    • GO:0005634 Nucleus
      A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
    • GO:0005634 Nucleus
      A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
    • GO:0005654 Nucleoplasm
      That part of the nuclear content other than the chromosomes or the nucleolus.
    • GO:0005829 Cytosol
      The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
    • GO:0005886 Plasma membrane
      The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

    Molecular function (1)

    None predicted

    Biological process (2)

    • GO:0072332 Intrinsic apoptotic signaling pathway by p53 class mediator
      A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
    • GO:0072332 Intrinsic apoptotic signaling pathway by p53 class mediator
      A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.

    Protein Sequence

    >Q62415
    MMPMILTVFLSNNEQILTEVPITPETTCRDVVEFCKEPGEGGCHLAEVWRGSERPIPYDHMMYEHLQKWGPRREEVKFFL
    RHEDSPTESSEQGARQTQEQRTQRSVVNVPGEKRTENGVGNPRVELTLSELQDMAARQQQQIENQQQMLVAKEQRLHFLK
    QQERRQQQSVSENEKLQKLKERVEAQENKLKKIRAMRGQVDYSKIMNGNLSAEIERFSAMFQEKKQEVQTAILRVDQLSQ
    QLEDLKKGKLNGFQSYNGRLTGPAAVELKRLYQELQIRNQLNQEQNSKLQQQKELLNKRNMEVAMMDKRISELRERLYGK
    KIQLNRVNGTSSPQSPLSTSGRVAAVGPYIQVPSTGGFPLPGDPVKPQSLTIASSAAHGRSKSANDGNWPPLKQNSASVK
    STQMTGDWKDSGMEGTLKQGAISSQPLPLSALGATEKLGIEIGKGPPPIPGVGKPLPPSYGTYPSSGPLGPGSTSSLERR
    KEGSLPRPGAGPPSRQKPAPLPPASNAPQPGSSQQIQQRISVPPSPTYPPAGPPAFPTGDGKPELPLTVAIRPFLADKGS
    RPQSPRKGPQTVNSSSIYSMYLQQATPPKNYQPPAHGTLNKSVKAVYGKPVLPSGSASPSPLPFLHGSLGTGTAQPQPPS
    DSAEKEPEQEGPSVPGEGSTVESLPRPLSPTKLTPIVHSPLRYQSDADLEALRRKLANAPRPLKKRSSITEPEGPGGPNI
    QKLLYQRFNTLAGGMEGTPFYQPSPSQDFVGTLADMDNGNTNANGNLDEPFPPRPTAPLPEELAPSSDANDNELPSPEPE
    ELICPQTTHQTAEPTEDNNNNVAPVPSTEQIPSPVAEAPSEEDQVPPAPLSPVIHPPAASASKRTNLKKPNSERTGHGLR
    VRFNPLALLLDASLEGEFDLVQRIIYEVEDPSKPNDEGITPLHNAVCAGHHHIVKFLLDFGVNVNAADSDGWTPLHCAAS
    CNSVHLCKQLVESGAAIFASTISDIETAADKCEEMEEGYIQCSQFLYGVQEKLGVMNKGTVYALWDYEAQNSDELSFHEG
    DAITILRRKDENETEWWWARLGDREGYVPKNLLGLYPRIKPRQRTLA